Symbol
Name
ID

Trp53bp2
transformation related protein 53 binding protein 2
MGI:2138319

Phenotype annotations related to nervous system

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

intracranial hemorrhage

intraventricular hemorrhage

increased neuron apoptosis

abnormal neuron differentiation

abnormal neuronal migration

abnormal neuronal precursor proliferation

abnormal neural tube morphology

abnormal embryonic neuroepithelium morphology

spina bifida

craniorachischisis

wavy neural tube

abnormal pineal gland morphology

absent pineal gland

abnormal brain morphology

abnormal cortical plate morphology

abnormal cortical ventricular zone morphology

hydrocephaly

enlarged brain ventricles

abnormal lateral ventricle morphology

abnormal choroid plexus morphology

dilated brain ventricle

abnormal cerebral cortex morphology

abnormal stratification in cerebral cortex

abnormal olfactory bulb morphology

abnormal embryonic/fetal subventricular zone morphology

exencephaly

increased neuronal precursor cell number

absent abducens nerve

abnormal trigeminal nerve morphology

abnormal dorsal root ganglion morphology

abnormal spinal cord central canal morphology

abnormal embryonic neuroepithelial cell proliferation

increased embryonic neuroepithelial cell proliferation

Availability

Mouse Genotype

Trp53bp2^tm1Xlu/Trp53bp2^tm1Xlu

Trp53bp2^tm1Xlu/Trp53bp2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23